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filingDate 2012-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2014-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20140043934-A
titleOfInvention Method for Purifying Fc-Fused Protein
abstract The present invention generally relates to a method for purifying Fc-fusion proteins produced in eukaryotic cell expression systems. More specifically, the present invention provides a stable, scalable, downstream purification process suitable for use in the preparation of TNFR: Fc for human administration, which is performed in an optimized Protein A affinity chromatography step and in both binding and eluting manner. Two ion exchange chromatography steps operated.
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priorityDate 2011-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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