| abstract |
The present invention provides antibodies that bind to ADP-ribosyl cyclase 2. Also provided are nucleic acid molecules encoding expression antibodies, expression vectors, host cells and methods of expressing antibodies. Antibodies are human cancers including acute myeloid leukemia (AML), B-cell chronic lymphocytic leukemia, breast cancer, colorectal cancer, kidney cancer, head and neck cancer, lung cancer, ovarian cancer and pancreatic cancer and asthma, gout, Crohn's disease, lupus, multiple It can be used to treat human inflammatory diseases including sclerosis, rheumatoid arthritis, psoriasis, diabetes and atherosclerosis. |