http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140041689-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36780e8e5afeaf55eb7ef9950cc8fe4d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64 |
| filingDate | 2012-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c37402022e3bde05f8bb6abb7710d14e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a36d191bc21473bacb4ab7ce502a6cec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79f5888a1723bd443ccdfe3fcfd6d20 |
| publicationDate | 2014-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20140041689-A |
| titleOfInvention | Β-hairpin peptide mimetics as CXC4 antagonists |
| abstract | There is a disulfide bond between Cys 4 and Cys 11 , wherein Xaa 3 , Xaa 7 , Xaa 8 , Xaa 13 and Xaa 14 are amino acid residues of the defined type defined in the description and claims, wherein the general formula cyclo (-Tyr 1 -His Β-hairpin of 2 -Xaa 3 -Cys 4 -Ser 5 -Ala 6 -Xaa 7 -Xaa 8 -Arg 9 -Tyr 10 -Cys 11 -Tyr 12 -Xaa 13 -Xaa 14 -D Pro 15 -Pro 16- ) Peptide mimetics, and pharmaceutically acceptable salts thereof, have beneficial pharmacological properties and are used to prevent HIV infection in healthy individuals or to slow or stop viral progression in infected patients; Or if the cancer is mediated or caused by CXCR4 receptor activity; When an immune disease is mediated or caused by CXCR4 receptor activity; To treat immunosuppression; Or while performing a constitutive collection of peripheral blood stem cells; And / or as agents for inducing recruitment of stem cells to regulate tissue repair. Such peptide mimetics can be prepared by methods based on hybrid solid phase and liquid phase synthesis strategies. |
| priorityDate | 2011-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 248.