| abstract |
(Problem) Providing excellent treatment or prevention of cardiovascular disease based on cGMP production enhancing action by soluble guanylic acid cyclase activating action. (Methods) An imidazopyridine compound having a carbamoyl group at the 3 position of the imidazo [1,2-a] pyridine skeleton and a substituent bonded to the 8 position via an oxygen atom is used for a strong soluble guanylic acid cyclase activating action. The present invention has been completed by finding out that cGMP production enhancer action can be obtained, and soluble guanylic acid cyclase can be an excellent treatment or prophylactic agent for various cardiovascular diseases. |