| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1077 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-34 |
| filingDate |
2012-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49a108b463e8d5cfc8d28f8f2832423e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc1c5dcfbbbf59888f4803b170453758
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b859630b74c7ccb14738d2a4f0d3195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31343ad81f9975e0db55ab677bb96fd5 |
| publicationDate |
2014-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20140038517-A |
| titleOfInvention |
Method for Purifying Diphtheria Toxin in Natural or Mutant Forms |
| abstract |
The present invention relates to the use of hydroxyapatite chromatography and multimodal chromatography to purify diphtheria toxin or mutant forms thereof from a mixture, eg, a host cell fermentation mixture containing impurities such as host cell proteins and DNA. . The invention also relates to integrating the method into a multi-step procedure with other diphtheria toxin purification fractionation methods suitable for in vitro and in vivo applications. |
| priorityDate |
2011-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |