| abstract |
The compounds of formula ( I ), or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, are inhibitors of TrkA kinases and also TrkA kinases such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases, and the like. Useful in the treatment of diseases that can be treated with inhibitors: Wherein R 1 , R 2 , R a , R b , R c , R d , X, Y, B and ring C are as defined herein, YB moiety and NH-C (= X) The -NH moiety is a trans conformation. |