| abstract |
The benzoxazepine compound of formula (I), its stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts, include those that inhibit the δ isoform of PI3K, and diseases mediated by lipid kinases such as inflammation, immunological Useful for the treatment of diseases and cancers. A method of using a compound of formula (I) is disclosed for in vitro, in situ and in vivo diagnosis, prophylaxis or treatment of a disease, or related pathology in mammalian cells: Formula I |