Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-175 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
filingDate |
2012-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ff8b475d6ea51c6f35bd3c28d740de9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3c9c672de1a4bbb331218556997b9a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8955cc0bf5f302c1653d9ec0c81b0923 |
publicationDate |
2014-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20140029475-A |
titleOfInvention |
CSF-1R Inhibitors for the Treatment of Brain Tumors |
abstract |
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof and a composition containing said compound for use in treating brain tumors, in particular glioblastoma. The present invention provides effective brain tumor therapy and can be used by oral administration of a compound of formula (I) as further described herein. Also disclosed are genetic signatures that correlate with successful therapies using the method: (I) In this formula, R 1 is alkyl pyrazole or alkyl carboxamide and R 2 is hydroxycycloalkyl. |
priorityDate |
2011-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |