| abstract |
The present invention relates to (1) a biguanide compound or a pharmaceutically acceptable salt thereof; (2) 2-deoxy-D-glucose or a pharmaceutically acceptable salt thereof; And (3) an anticancer composition comprising 5-hydroxymethylfurfural or a pharmaceutically acceptable salt thereof and / or citric acid or a pharmaceutically acceptable salt thereof as an active ingredient , And food compositions for the prevention or amelioration of cancer. The anticancer composition of the present invention is a synergistic combination of 5-hydroxymethylfurfural, metformin, phenformin, 2-deoxy-D-glucose and citric acid, Can inhibit the survival of cancer cells and can inhibit the cell cycle of cancer cells without inducing toxicity to normal cells and induce the death thereof. Therefore, it can be effectively used as an anticancer drug without side effects. |