http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140025563-A

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filingDate 2014-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73afb921157c83d7103356019c44af73
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publicationDate 2014-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20140025563-A
titleOfInvention Human sweet receptors T1R2 and T1R3 without membrane transmembrane sites and methods for expression and purification thereof
abstract The present invention relates to a human sweet taste receptor T1R2 or T1R3 in which the transmembrane domain is removed and a method for expressing and purifying it. According to the method of the present invention, by expressing the human sweet taste receptor T1R2 or T1R3 in a state in which the membrane passage region is removed, the protein is easily expressed and purified due to an increase in the water solubility of the protein, It is expected to be very useful for the study of action and the mechanism of sweetness signaling.
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