http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140025378-A

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publicationDate 2014-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20140025378-A
titleOfInvention Cinnamomum Burmani Extract, Extraction Method, and Use thereof as Proton Pump Down-Regulators, Enzyme Inhibitors and Mucosal Protectors
abstract Extracts and / or fractions (DLBS2411) derived from Cinnamomum Burman associated with extraction methods and biological activity exhibit activity as antiulcers by protecting the mucosa and down-regulating H + / K + ATPase. Treatment with DLBS2411 reduces H + / K + ATPase mRNA levels in HEK 293 cells and gastric parietal cells. In addition, DLBS2411 inhibits the activity of H + / K + ATPase gastric enzymes, where pH affects this inhibitory mechanism. DLBS2411 also features as an antioxidant, evidenced by increased reducing power as the dose administered increases.
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