http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140017238-A

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filingDate 2012-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aebb29d8c1b30c4edeef59486dbdd282
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publicationDate 2014-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20140017238-A
titleOfInvention A pharmaceutical composition and health functional food for preventing or treating thrombosis, comprising an extract of Angelicae gigantis as an active ingredient
abstract The invention ildanggwi (Angelica The present invention relates to a pharmaceutical composition and a health functional food for preventing or treating thrombosis containing an extract of acutiloba as an active ingredient and more particularly to a pharmaceutical composition for preventing or treating thrombosis, And to a health functional food comprising the extract. The pharmaceutical composition for the prevention or treatment of thrombosis of the present invention and the hyperproliferative extract as an active ingredient of the health functional food can be prepared by extracting the underside of the hypercholesterol with ethanol or the like to prepare an extract, After the fractionation, the fraction was sequentially fractionated using ethyl acetate. Among these, the ethyl acetate fraction showing the antithrombotic activity by the excellent anticoagulant effect has an effect of effectively inhibiting thrombogenesis, There is an excellent effect that can be used for prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke. In particular, the crude extract of the present invention does not exhibit acute oral toxicity, has excellent thermal stability, and does not show any loss of blood coagulation factor inhibition and activation effect even in an acidic condition of pH 2 and in plasma. Thus, the extract, powder, And it can be prepared in a form that can be taken at any time. Therefore, it is a very useful invention in the pharmaceutical industry and the food industry.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016172711-A
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