abstract |
The present invention relates to a nucleic acid molecule comprising at least one internal element of a functional promoter of herpesvirus, a functional enhancer of herpesvirus, and a CpG island of the aprt (adenine phosphoribosyl transferase) gene and / or its functional variant. It is about. Also disclosed are methods of making the desired polypeptide using the nucleic acid molecule, the vector containing the nucleic acid molecule, and the host cell. |