abstract |
Compounds selected from pyrimidine conjugated derivatives of Formula 1, pharmaceutically acceptable salts thereof, optical isomers, hydrates, and solvates thereof have excellent inhibitory activity against FMS kinases, and thus pharmaceutical compositions comprising the same It is excellent in preventing or treating an immunological disease, metabolic disease, inflammatory disease, and cancer caused. Formula 1 In the above formula, A, X, Y, R 1 , R 2 , and R 3 are as defined in the specification. |