Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ceade2c819755776ca6384a510c32dba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D10B2509-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F6-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D02G3-448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-44 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F6-92 |
filingDate |
2012-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a5dd62ac1be4ebf5b01fc9dd9470126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecaa85cffd129c3ee166bd55bc2631d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72c02761c1203d23d9974dbc28cd9beb |
publicationDate |
2013-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20130141805-A |
titleOfInvention |
Electrospinning of Polymer and Drug Mixtures |
abstract |
Nano-sized pores formed between the electrospun nanofibers can provide oxygen, nutrients, growth factors, and the like to the tissue. The present invention relates to the structure of electrospun nanofibers of primary poly (L-lactide-co-caprolactone-co-glycolide) (PLCG). An amphoteric interpolymer containing phosphorylcholine group (PMB30W) and an anti-proliferative substance (rapamycin) and soluble in water is added to the PLCG by solvent mixing and subsequent electrospinning. The nanostructure of electrospun PLCG / PMB30W / rapamycin mixed fibers is stable during incubation in phosphate buffer solution without chemical crosslinking. The amphoteric properties of PMB30W and hydrophobic rapamycin naturals allow electrospun PLCG / PMB30W / rapamycin blended fibers to be stable under physiological conditions. Electrospun PLCG / PMB30W / rapamycin blend fiber will be better for artificial organs of tissue engineering. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160069276-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114129762-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114129762-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020175736-A1 |
priorityDate |
2012-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |