| abstract |
The present invention provides a dried powder comprising salmeterol ginafolate, fluticasone propionate and tiotropium bromide, and a carrier as pharmacologically active ingredients; And inhalation formulations comprising the same, wherein the dry powder inhalation formulations sufficiently reach the three pharmacologically active ingredients at a target site upon inhalation, have excellent content uniformity, and less change in dynamic particle distribution depending on flow rate change, It is useful for the prevention or treatment of respiratory diseases, especially asthma and chronic obstructive pulmonary disease (COPD). |