http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130139314-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b36e802ae3429bbce43513b03fc1419a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0008 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-0613 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-525 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F9-01 |
filingDate | 2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_936e71ac0a1d519e036e6e0dd2ad174b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cbaeb8032be1ad24070a6a1ffec122d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63172ba3c95caf00eefa7f3df127ce4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05c1b2f59cc1e144de13d13e8a229bbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdad71a600d0cb5e32ce94892cccf091 |
publicationDate | 2013-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20130139314-A |
titleOfInvention | Corneal delivery device and method of riboflavin by ion transport for keratoconus |
abstract | The present invention is directed to a reservoir (8) containing a riboflavin solution suitable only to be placed in the eye; An active electrode 2 disposed in or on the reservoir 8; Passive electrodes suitable for placement on the subject's skin elsewhere in the body, preferably near the eye, such as the forehead, cheek or neck; A combination of means 10 for irradiating the corneal surface with a suitable light, such as ultraviolet light, to obtain corneal crosslinking after delivery of the drug or riboflavin, wherein the reservoir 8 and the active electrode 2 are ultraviolet and / Or an iontophoresis device for delivering any ionized chemical solution, such as a riboflavin solution, to the cornea, which is transparent to visible and / or infrared light. The present invention Positioning said iontophoresis device comprising a reservoir containing a riboflavin solution in the eye to be treated; Driving a solution motion by applying a cathode current for 0.5 to 5 minutes, with an intensity of 2 mA or less; Immediately after the end of current application, the corneal surface is irradiated with ultraviolet light for 5 to 30 minutes at a power of 3 to 30 mW / cm 2 ; Thereby obtaining corneal crosslinking of riboflavin Delivery of any ionized drug solution, such as riboflavin solution, to the cornea for the treatment of keratoconus or any other dilated corneal disease or for enhancing corneal interstitial structure, using an ocular iontophoresis device, It is about a method. |
priorityDate | 2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.