| abstract |
The present invention relates to an epitope for converting novel T cells into T H 2 cells (Helper T cell 2), specifically, the extracellular domain of the activation-inducible tumor necrosis factor receptor (AITR). Epitopes having amino acid positions 20-30 (SEQ ID NO: 2), an antibody recognizing the epitope, a polynucleotide encoding the epitope, a polynucleotide encoding the antibody, an expression vector comprising the polynucleotide, the vector A transformant, a composition for converting T cells into T H 2 cells, comprising the antibody, and a method for converting the same; a pharmaceutical composition for preventing or treating autoimmune diseases, including the antibody, and the antibody It relates to a method of treating autoimmune diseases. |