abstract |
The present invention relates to compounds, compositions, and methods for research, diagnosis, and treatment of traits, diseases, and conditions that respond to and / or modulate HBV gene expression and / or activity regulation. Specifically, the present invention relates to small nucleic acid molecules, such as short interfering nucleic acids (siNA), short interfering RNAs (siRNA), double stranded RNA (dsRNA), which may or may mediate RNA interference (RNAi) for HBV gene expression. , Double-stranded nucleic acid molecules, including micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules. |