| abstract |
Fibronectin type III (FN3), such as the tenth FN3 repeat from human fibronectin (human tenacin), including isolated nucleic acids encoding proteins scaffolds, vectors, host cells, and methods of making and using the same. A protein scaffold based on the consensus sequence of the protein. The protein scaffold molecules of the present invention provide enhanced six modifiable loop domains that can be engineered to form binding partners capable of binding to targets for application in diagnostic and / or therapeutic compositions, methods and devices. Thermal and chemical stability. |