Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbffa3b81b3b862dc7220b5648f5f745 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-10041 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2012-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5f121c507ea494802028728f27b2eac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_663eb11b9cd768eb2fad93bc12155870 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16c2b0a30d54c5e9e049ca5e4157cb40 |
publicationDate |
2013-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20130118080-A |
titleOfInvention |
Method for producing dedifferentiated stem cells using intracellular protein transfer |
abstract |
The present invention relates to a method for producing a stem cell with a high efficiency of non-EE using a protein-secreted amino acid sequence of a homeode domain in the intracellular introduction of a degenerating stem cell inducer, A transfected cell expressing a fusion protein of a secretion-permeation-related site and a dedifferentiation inducer capable of migrating into a cell is prepared and co-cultured with the somatic cell of the differentiated cell, whereby the cell is transformed by a dedifferentiation factor Since the dedifferentiated stem cells have been prepared from the somatic cells, the gene construct encoding the fusion protein of the present invention and the transformant cells expressing the same are useful for preparing undifferentiated stem cells from differentiated somatic cells have. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9249385-B1 |
priorityDate |
2012-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |