| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2534bb9f13460c6429c25acf8df25d0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 |
| filingDate |
2011-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f616039b3c24a0a71a3f9cafca73371d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8393b267bb6321acd51aa0b83f0187a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_113d718403f4e1219b6b7827997dd8b7 |
| publicationDate |
2013-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20130113348-A |
| titleOfInvention |
Particulate coating formulation |
| abstract |
In oral fast disintegrating tablets containing 2- (3-cyano-4-isobutyloxyphenyl) -4-methyl-5-thiazolecarboxylic acid as an active ingredient, the stimulation in the oral cavity and the pharynx is not substantially felt. In addition, the present invention provides a formulation in which good elution property and oral disintegration property are maintained even under preservation under high temperature and high humidity conditions. Nuclear particles containing 2- (3-cyano-4-isobutyloxyphenyl) -4-methyl-5-thiazolecarboxylic acid are covered with a layer containing methacrylic acid copolymer and further at 40 ° C. 2- (3-cyano-4-isobutyl) 10 minutes after the elution test evaluated by 50 rotations per minute (test solution: pH 6.0 McIlvaine buffer) per minute after storing for 2 weeks under the conditions of / 75% RH opening. A fast disintegrating tablet in the oral cavity containing particles overcoated with a layer containing a water-soluble sugar having an elution rate of oxyphenyl) -4-methyl-5-thiazolecarboxylic acid of 70% or more. |
| priorityDate |
2010-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |