| abstract |
The present invention relates to a compound represented by the following formula (I), a pharmaceutical or cosmetic composition comprising the same, and a use as an AGE-inhibitor for capturing a reactive carbonyl compound, wherein X is CH 2 , C═O, C = S, Or CHOH, X is CH 2 , C═O, C = S, or CHOH, R 1 is optionally substituted with one or more halogen atoms, preferably with fluorine (F) atoms, or with one or more CF 3 groups, n is 1 or 2, or X is CH 2 , C═O, C = S, or CHOH, R 1 is a peptide comprising two amino acids, each amino acid optionally containing one or more halogen atoms, preferably Is substituted with a fluorine atom or substituted with one or more CF 3 , n is 0 or 1, XR 1 is PO 3 H or SO 3 H, and n is 0, 1 or 2; R 2 is H, XR 1 , C 1 -C 6 alkyl group, C 1 -C 6 araalkyl group or aryl group, wherein the alkyl group, araalkyl group and aryl group are amine (NH 2 ), carboxyl group (COOH), one At least one halogen atom, preferably a fluorine atom, or at least one CF 3 ; Or pharmaceutically acceptable addition salts, isomers, enantiomers, and diastereomers of the compounds, mixtures thereof: |