Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d0fc2b70675ee19bd5fc464f5ae9061 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-97 |
filingDate |
2012-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_690ecd66d6896b0da1e55ed761a474cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2ed971d08edbaf49c56a914f6e80890 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98119cd11024955f616c14ae9553cc37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73879f38c75478458b5b8fc3132efdf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0205f3495f5cbe1ea0a4c863131344f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e981ed0b3439b87c8efa1d7a0f56cf74 |
publicationDate |
2013-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20130109874-A |
titleOfInvention |
Crosslinking inhibitor of the final glycation end product containing disubstituted acid as an active ingredient and disintegrant |
abstract |
The present invention relates to a crosslinking inhibitor and a disintegrant pharmaceutical composition containing chebulic acid as an active ingredient, inhibiting the formation of crosslinks between the final glycation product and the protein and decomposing the formed crosslinks. According to the present invention, since chebulic acid not only inhibits the formation of cross-links between the already formed final glycated product and the protein, but also has an effect of degrading, it inhibits the structural change of proteins such as collagen and elastin in tissues. And improve and thereby reduce or treat the incidence of the disease. |
priorityDate |
2012-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |