| abstract |
The present invention relates to a cyclodextrin, poly (maleic anhydride), and a hydrophobic drug delivery complex to which a hydrophobic drug is bound, and a pharmaceutical composition comprising the same as an active ingredient. The hydrophobic drug delivery complex according to the present invention can effectively control the release and delivery rate of hydrophobic drugs as well as control the physical / chemical binding and / or composition of cyclodextrins, poly (maleic anhydride), and hydrophobic drugs, Significantly increased solubility can increase the efficacy of the drug. In addition, the hydrophobic drug can be variously changed, and since the peptide having a target orientation can be introduced freely on the surface of the complex, it can be applied to the treatment of various diseases as well as cancer treatment. |