http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130104166-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ebb6665c470e905eb712ad48a9495ac |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
| filingDate | 2012-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34adc2a2376787c88832dfef888fc418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7abbe0371af38ef148276ffbc9aa30a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8d6c8e8fbb0acdebd4910a3288a8be7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd1eb88e6ea1dc69262d5ce9e81093f4 |
| publicationDate | 2013-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20130104166-A |
| titleOfInvention | Composition for inducing bone differentiation of stem cells and method for increasing bone differentiation using the same |
| abstract | The present invention is to increase the differentiation-inducing effect of inducing osteoblast differentiation of stem cells comprising a synthetic peptide or homologs thereof for promoting bone differentiation and bone formation consisting of amino acid sequences derived from bone-forming protein as an active ingredient The composition or the pharmaceutical composition for inducing bone differentiation, and a medium composition comprising the same, and a method for increasing bone differentiation using the same, the synthetic peptide for inducing bone differentiation of stem cells of the present invention comprises the amino acid sequence of SEQ ID NO: 1 to 20 Branches are composed of one or more peptides or homologs selected from CP1, CP2, CP3, CP4, CP5, CP6, CP7, CP8, CP9, CP10, CP11, CP16, CP20, CP22, CP23, CP25, CP27, CP28, CP29, CP30 It is characterized by. The composition for inducing osteogenic differentiation of the present invention constituted as described above provides a synthetic peptide for promoting bone formation having a specific sequence and the synthetic peptide has a remarkable effect in promoting the differentiation of stem cells (MSCs) into osteoblasts The pharmaceutical composition of the present invention comprising the synthetic peptide as an active ingredient is excellent in the treatment of osteoporosis, bone defect disease and / or osteoarthritis, and thus can replace the expensive BMP in the past, The increase method is a useful invention which can induce bone differentiation easily and inexpensively. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104337987-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104800777-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104984291-A |
| priorityDate | 2012-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 174.