http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130103301-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae372ddaa494f2face39592b0429cc16 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 |
filingDate | 2011-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_266f9ece8852cc61ea5b4055fd8f90fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50608047928ec4e4faef2f536ca2a7a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29ffbe128c596c44b323b81058f20e7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d40da8461c7dbf5866d9dee7f5b0e282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb28b7e715c4924c147a0f50dc6cc6ba |
publicationDate | 2013-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20130103301-A |
titleOfInvention | TF-JPP that specifically binds to transcription factors |
abstract | The present invention provides a method for preparing a stabilizing region comprising: (a) a structure stabilizing region comprising parallel, antiparallel or parallel and antiparallel amino acid strands formed with interstrand noncovalent bonds; And (b) TF-target binding region I and TF-target binding region II, each of which is bound to both ends of the structure stabilization site and comprises randomly selected n and m amino acids, respectively. TF-bipodal peptide binder that specifically binds to TF comprising TF-target binding region II), wherein the TF-bipodal peptide binder of the present invention has a very low level (eg, nM level) relative to TF K D values (dissociation constants) are shown, indicating a very high affinity to the TF target. The TF-bipodal peptide binder of the present invention can be used not only for use as a medicament but also for in vivo molecular imaging and drug delivery targeting, and can also be very useful as an escort molecule. |
priorityDate | 2010-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 808.