| abstract |
Pyridones and pyrazinone compounds of formula (I), including their stereoisomers, tautomers and pharmaceutically acceptable salts, which are useful for inhibiting Btk kinases and for treating immune disorders such as inflammation mediated by Btk kinases. . Vitro of such disorders in mammalian cells, or associated pathological conditions (in in vitro ), in situ ( in situ ) and in vivo ( in In vivo ) methods of using the compounds of formula (I) in diagnosis and treatment are disclosed . (I) |