http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130101952-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14430ce0c28e36044927f5834e4d02ad |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6823 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6844 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_120d223f37d6893c0f2924f518c3fc54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34ac7f5c13a90df324db97c714067048 |
publicationDate | 2013-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20130101952-A |
titleOfInvention | Detection of Target Nucleic Acid Sequences Using PTO Cleavage and Extension-Dependent Hybridization |
abstract | The present invention relates to the detection of target nucleic acid sequences using PTO cleavage and Extension-Dependent Hybridization (PCEH). The present invention does not use a probe that hybridizes directly with a target nucleic acid sequence to provide a target signal, but forms an extended strand synthesized by template CTO having an artificially selected sequence depending on the presence of the target nucleic acid sequence and is specific thereto. As an alternative, probes that hybridize are used. The present invention uses a PTO that primarily detects a target nucleic acid sequence, and uses a SO that hybridizes with a target-dependent extension strand to provide a signal, thereby maximizing specificity and irrespective of the target nucleic acid sequence. It is easy to set the reaction condition because the signal generating condition can be adjusted. This feature makes it possible, in particular, to easily set signal response conditions and to prevent false positive signals in the detection of simultaneous multi-target nucleic acids in clinical samples with various aspects. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10364459-B2 |
priorityDate | 2012-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 167.