Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34bd4e87ecbca17f16d460ca394e60f9 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate |
2011-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_300f262109a5ded69797a47e6549e6aa |
publicationDate |
2013-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20130097202-A |
titleOfInvention |
Modulation resistant dosage forms comprising inorganic salts |
abstract |
The present invention relates to a pharmaceutical dosage form exhibiting a breaking strength of at least 500N, the dosage form comprising a pharmacologically active ingredient (A); Inorganic salts (B); And a polyalkylene oxide (C) having a weight average molecular weight of at least 200,000 g / mol, wherein the content of the polyalkylene oxide (C) is at least 20% by weight based on the total weight of the dosage form. To; Wherein the pharmacologically active ingredient (A) is present in a controlled-release matrix comprising the inorganic salt (B) and the polyalkylene oxide (C), and under in vitro conditions, the pharmacological activity from the matrix The release profile of component (A) comprises at least a time interval during which release follows zero order kinetics. |
priorityDate |
2010-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |