| abstract |
The following general formula (II), (In formula, R < 11> and R < 12> shows a hydrogen atom and other C1-C8 alkyl groups, R < 13> shows a hydrogen atom and a C1-C8 alkyl group other, R < 14> a C1-C8 alkoxy group, The heterocyclic group which may have a hydroxyl group, a cyano group, or a substituent is shown, and Represents naphthalene ring, etc.) Or a pharmacologically acceptable salt thereof is used as a P2X 4 receptor antagonist. |