http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130091822-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95363fc2cf0b49e7a4aef32d7cb692a1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D06M11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M11-00 |
| filingDate | 2012-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_281553822c2e28f22374c30d7298038e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8af807cff7c10fa9fbe99818ecd1517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_133f3215c3795b68a7e6bebbf9cac415 |
| publicationDate | 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20130091822-A |
| titleOfInvention | Method for producing a fibrous skeleton composed of electron-spun porous PIPE fibers |
| abstract | For bone tissue engineering studies, many different types of skeletons were fabricated using different methods. Here, new fibrous frameworks have been continuously studied for the regeneration of bone tissue defects. This porous PCL fiber-based fibrous backbone is made using the appropriate solvent of the two solvents in the electrospinning process. As a porous structure, CaP particles were easily coated on fibers after immersion in simulated body fluid (SBF) solution. Morphology, structure, CaP coating, and wettability were investigated by mass spectrometry and contact angle analysis by SEM, EDS, X-ray, and TEM techniques. The proliferation of cells in vitro and the interaction of cells in the fibrous skeleton were investigated. In addition, CaP coatings based on non-porous PCL fiber-based, porous PCL fiber-based, and porous PCL fibers, including the fibrous skeleton's ability to form bones in vivo, were also investigated. By measuring in vitro results, we found that after 12 hours of immersion in SBF (Ap-dPCL12), the fibrous scaffold based on porous PCL fibers was superior to the interaction, growth and proliferation of MG-63 osteoblasts. In vivo analysis showed that the Ap-dPCL12 fibrous framework accelerated bone formation faster than the fibrous framework based on nonporous and porous PCL fibres. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111005082-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115068681-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115068681-B |
| priorityDate | 2012-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.