| abstract |
The present invention relates to novel crystalline acid addition salts or trihydrates thereof of tricyclo derivative compounds and methods for their preparation. In the case of the crystalline acid addition salt or the hydrate thereof according to the present invention, it is very useful for maintaining the quality during drug preparation because it is stable to moisture as it is stable to moisture, as well as PARP (poly (ADP-ribose) polymerase) Neuropathic pain caused by hyperactivity, epilepsy, stroke, Alzheimer's disease, Parkinson's disease, Amyotrophic axon sclerosis (ALS), Huntington's disease, schizophrenia, chronic and acute pain, ischemic brain injury, neuronal loss after hypoxia It can be usefully used as a pharmaceutical composition for the treatment of trauma and nerve damage. |