| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98fa76d4439f5bacf7da7246ac8065f8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0455
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C21-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C21-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2012-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_134039958745b8296c904b72631de490
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac5cb5e3cb5604688d6740e1fc3efd1a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b50a6854015ae433c2f7bc7697d5289b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b47eded86fec806736abf417c659228
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f563a6601c78381f0afe1b23ecc0def8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0df2fb6f2184934d421effd04dc49ccd |
| publicationDate |
2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20130087821-A |
| titleOfInvention |
Preparation of Fluorine-18 Eluent with Hydrogen Ion Concentration Control and Labeling Method for Fluorine-18 Using the Eluent |
| abstract |
The present invention relates to a method for labeling radioisotope fluorine-18, and more particularly to a method for preparing an organic [ 18 F] fluoro compound by reacting an alkyl halide or alkyl sulfonate with [ 18 F] fluoride. In addition, a base used to elute [ 18 F] fluoride supported on the quaternary alkylammonium polymer support using a solution containing a metal salt or quaternary ammonium salt of which hydrogen ion concentration is controlled by the method of Representative FIG. 3. It relates to a [ 18 F] fluoride labeling method characterized in that there is no. The present invention accurately reflects the concentration of base necessary for the nucleophilic substitution of [ 18 F] fluoride using a hydrogen ion concentration controlled [ 18 F] fluoride eluent, or after elution of [ 18 F] fluoride It is possible to stably obtain a compound labeled [ 18 F] fluoride in high yield by allowing the labeling reaction to be performed without a base, which is useful for the production of radiopharmaceuticals labeled with fluorine-18. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10525151-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016072801-A1 |
| priorityDate |
2012-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |