http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130078549-A

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filingDate 2011-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2510ebe7c53bdf6fe91957cb0f5bd48
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publicationDate 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20130078549-A
titleOfInvention On-site crosslinked hydrogel composed of gamma-polyglutamic acid and its preparation method
abstract TECHNICAL FIELD The present invention relates to a biodegradable and biocompatible hydrogel which can be used as a sealant for inhibiting leakage of blood or air during surgical operation, a tissue adhesive, an adhesion inhibitor, a drug delivery carrier, etc., During the operation, the solution is kept in the aqueous solution for a certain period of time, so that the solution is not required to be used immediately. The gel is formed immediately from the wound site, and the adhesive force to the biotissue is excellent, so that leakage of blood or air is suppressed, and it is decomposed and absorbed or discharged in the living body, and there is no toxicity to the living body. The gelation time can also be adjusted and controlled to a desired degree. Therefore, the hydrogel can be used preferably for various purposes such as biotissue bonding and the like.
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