| abstract |
The present invention relates to a composition for inhibiting 15-hydroxyprostaglandin dehydrogenase (15-PGDH) containing a plant extract as an active ingredient. The 20 plant extracts of the present invention inhibit 15-PGDH, which is a key substance for inactivation of PGE 2 , and have a low cytotoxicity, such as scalp diseases such as hair loss caused by 15-PGDH, peptic ulcer, stomatitis or oral cavity It can be usefully used for the prevention or treatment of ulcers, wounds and burns, fractures or peripheral vascular diseases. |