| abstract |
The present invention relates to a 2-hydroxyarylamide derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof and a pharmaceutical composition for preventing or treating cancer containing the same as an active ingredient. Since the 2-hydroxyarylamide derivative compound prepared by the present invention has an excellent effect of inhibiting TMPRSS4 serine protease activity and inhibiting TMPRSS4 expressing cancer cell infiltration, cancer cells, in particular, colorectal cancer, lung cancer, breast cancer, prostate cancer, ovarian cancer, By inhibiting TMPRSS4 overexpressed in pancreatic cancer or gastric cancer cells, it can be usefully used as a composition for preventing or treating cancer. |