| abstract |
In general, despite containing ingredients familiar as ions that are present in food or in vivo and not toxic to the organism within a range of physiological concentrations, the allergy improvement, treatment or prevention of allergy is extremely safe and effective, Or a composition comprising a specific oligosaccharide and a divalent metal cation that is effective in a local inflammatory response. As an intercellular adhesion enhancer in epithelial cells, 1-ketose and / or nythose and divalent metal cations are active ingredients. According to the present invention, not only the inhibition of the inter-epithelial tight junction protein, which causes the invasion of the allergen into the body, but also the epithelial cell adhesion is enhanced by repairing or promoting the formation of the tight junction protein between the epithelial cells, Effective alleviation, treatment and prevention of allergic disease symptoms are possible. |