| abstract |
The present invention discloses methods and compositions for reducing serum parathyroid levels in, for example, patients with chronic kidney disease. In this method, a modified release formulation of 25-hydroxyvitamin D is administered orally in an effective amount to a patient suffering from secondary hyperparathyroidism to lower serum intact parathyroid hormone (iPTH) levels and to reduce total serum 25-hydroxy in serum. Prevent surge of oxyvitamin D |