http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130034640-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5351c62aee4203f2be2944f21a6def2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2012-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9742ea188614c8cc92888ca1f0ee263a |
| publicationDate | 2013-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20130034640-A |
| titleOfInvention | Composition for inducing apoptosis containing BASI protein |
| abstract | The present invention relates to a composition for inducing apoptosis comprising KAISO protein as an active ingredient, and to an agent for inhibiting or treating damage caused by genotoxicity. More specifically, a polypeptide having an amino acid sequence of SEQ ID NO: 2 It relates to a composition for inducing apoptosis comprising a nucleotide sequence encoding an amino acid sequence of (KAISO protein) or SEQ ID NO: 2 as an active ingredient, and a composition for inhibiting or treating damage due to genotoxicity. The present invention provides the function of KAISO as a master regulator of the p53 pathway associated with cell cycle arrest and apoptosis, and traps KAISO in the cytoplasm by p120ctn and a low molecular weight anticancer agent that can strongly induce KAISO. In this case, a method of treating cancer may be provided by securing an inhibitor of the interaction of KAISO-p120ctn. In addition, the present invention can provide a composition for inducing apoptosis comprising a KAISO protein as an active ingredient and a composition for inhibiting or treating damage caused by genotoxicity. |
| priorityDate | 2011-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 910.