| abstract |
The present invention (a) inner core (inner core); And (b) a nanocapsule including a shell surrounding the inner core, wherein the shell is formed by crosslinking of a nonionic polymer and albumin covalently bonded with a functional group. It relates to a nano capsule (nano capsule) and a method for producing the nano capsule, characterized in that. Unlike conventional polymer micelles and liposomes, the nanocapsules of the present invention can maintain and improve physical stability in vivo and encapsulate a transport target (eg, poorly soluble drugs and / or contrast agents, etc.) with high efficiency. In addition, unlike the conventional invention in which oil and organic solvents are used to transport poorly soluble substances, nanocapsules may be prepared including only a transport target for treatment. Therefore, the nanocapsules of the present invention can be usefully used in the formulation of injectables, and can be used for in vivo drug treatment and / or imaging by encapsulating poorly soluble drugs and / or contrast agents in a delivery target. |