abstract |
The present invention provides antibodies that interact with or bind to human B7 related protein-1 (B7RP1) and antibodies that neutralize its function by binding to B7RP1. The present invention also provides methods of neutralizing B7RP1 function by administering a pharmaceutical composition of said antibody, and a pharmaceutically effective amount of an anti-B7RP1 antibody, in particular for immune disorders (eg, inappropriate immune responses). Methods of calibration of B7RP1 in a sample using anti-B7RP1 antibodies are also provided. |