http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130020827-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb7ce8745175865c6357f7d5fe7fccf5 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
filingDate | 2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5ff4994b630ac8e8c3a66c87a9e6af7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a21193fd7b8b83b86867b2710b6ae2c |
publicationDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20130020827-A |
titleOfInvention | JPN / 3RHCOC macromolecular complex and method of using the same |
abstract | The present invention discloses a composition comprising a novel macromolecular assembly (PPRC complex) comprising PKN3, PDK1 and RhoC and a method of using the same. PPRC complexes have been shown to have kinase activity and have been found in cells of high malignancy potential, such as cells of particularly aggressive cancers. In some aspects, the present invention provides methods of screening for compounds with cancer therapeutic potential, methods for diagnosing aggressive cancer, methods for determining the prognosis of patients with cancer, classifying patients in clinical trials, or the effectiveness of certain treatment regimens. A kit is provided that includes a method of determining a protein, a polypeptide that controls the formation of a PPRC complex, and one or more components of the PPRC complex. |
priorityDate | 2009-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 755.