http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130011379-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73514a82d40d7976a333e6e11039ae41 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
| filingDate | 2011-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e4748c0e1aad2657e7cf75e81929e87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fde562ad5c75e1b3a0aa2a21e4e5bfde http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9a4143bcd1fcc2af471ebac668ac0f8 |
| publicationDate | 2013-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20130011379-A |
| titleOfInvention | Method for treating lung cancer using expression or activity inhibitors of adenine nucleotide translocator 2 |
| abstract | PURPOSE: A method for treating lung cancer using an inhibitor of adenine nucleotide translocator 2(ANT2) expression or activation is provided to suppress lung cancer cell growth and apoptosis. CONSTITUTION: A pharmaceutical composition for treating lung cancer contains adenine nucleotide translocator 2 small interfering RNA(ANT2 siRNA) or ANT2 short hairpin RNA(shRNA) as an active ingredient. The ANT2 siRNA or ANT2 shRNA induces ANT2 mRNA decomposition by binding an antisense sequence of sequence number 3 with a sense sequence of sequence number 1. The composition suppresses HIF-1 transcription and translation. The composition suppresses mTOR(mammalian target of rapamycin) mechanism under an hypoxic environment. A method for treating lung cancer comprises a step of administering ANT2 siRNA or ANT2 shRNA to a patient. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101872624-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014193159-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101384686-B1 |
| priorityDate | 2011-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.