| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_686f360c5896f7a2e7fab15401923ef4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2305-08 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-728 |
| filingDate |
2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55ccb41b38761a88c84a712ad97e1d95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_488b01eaeea118523b10f73997f501c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45ab24a60e7ac60cc6127fa1b9853dfc |
| publicationDate |
2013-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20130010973-A |
| titleOfInvention |
Method of prepairing crosslinked hyaluronic acid gel |
| abstract |
PURPOSE: A manufacturing method of a cross-linked hyaluronic acid gel is provided to easily manufacture a cross-linked hyaluronic acid gel with low crosslinked degree and excellent viscoelasticity. CONSTITUTION: A manufacturing method of a cross-linked hyaluronic acid gel comprises: a step of stirring and mixing a mixture which comprises hyaluronic acid, a crosslinking agent and water under an acid or alkali condition. The crosslinking agent is selected from divinylsulfone, 1,4-butanediol ยท diglycidylether, ethylene glycol, and diglycidylether. The concentration of the crosslinking agent is 0.02-1 w/v%. The storage elasticity(frequency 1 Hz) of the mixture before the crosslinking reaction is 15,000 Pa or more. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115279798-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150029578-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160038330-A |
| priorityDate |
2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |