http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120136660-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5351c62aee4203f2be2944f21a6def2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079 |
| filingDate | 2011-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4885b1232b91bc905221397524a041f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c8de5cfa4edef93a18757f71b3574e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d298f7c9920d6d7d53ded1ad10636bf |
| publicationDate | 2012-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20120136660-A |
| titleOfInvention | Method for producing midbrain specific dopamine neurons from undifferentiated stem cells |
| abstract | The present invention relates to a method for producing mesenchymal-specific dopamine neurons from embryonic stem cells, and more specifically (a) GSK-3 (glycogen synthase kinase-3) into undifferentiated cells that can be differentiated into neural cells. ) Treating the inhibitor; And (b) differentiating undifferentiated cells into dopamine neurons. The present invention relates to mesenchymal-specific dopamine neurons prepared by a method for producing midbrain-specific dopamine neurons from embryonic stem cells. According to the present invention, it is possible to produce midbrain specific dopamine neurons through tight control by infiltrating the low-bunba compound directly into cells based on the developmental mechanism of the animal compared to the conventional method. In addition, it is possible to prepare midbrain specific dopamine neurons without increasing the frontal or rear brain. It is expected to be a method for producing midbrain specific dopamine neurons for developing cell replacement therapeutics for cerebral nervous system diseases. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160053936-A |
| priorityDate | 2011-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 392.