| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb596f03d029321340c965e75de6564a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6921
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate |
2012-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a82f6cc86c31b0a09ff3a9670acd19c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd7d2bdea52102dddc5fb338d57acda3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e7d1be5cdbc9102f57b9982ab2dfefd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e23784fb02f4019cbd66516ed461cccf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0f37ac8b2b024f114fc11f53be0dbf7 |
| publicationDate |
2012-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20120135122-A |
| titleOfInvention |
Non-peptidyl Polymer-Insulin Multimers and Methods for Making the Same |
| abstract |
The present invention provides a non-peptidyl polymer-insulin multimer, wherein the non-peptidyl polymer and insulin covalently linked two or more non-peptidyl polymer-insulin conjugates are joined by cobalt ions to form a multimer. In the manufacturing method and manufacturing kit, a pharmaceutical composition for the prevention or treatment of diabetes comprising the multimer as an active ingredient, and a method for preventing or treating diabetes by administering the composition to a subject with or likely to develop diabetes It is about. The multimer of the present invention is not rapidly absorbed into the blood due to the large volume until it is separated into the monomer by natural dilution after subcutaneous injection, and thus a single dose of the drug can be administered, and the monomer is gradually separated into monomers. Useful for developing sustained insulin formulations. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140106455-A |
| priorityDate |
2011-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |