| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-85 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6901
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate |
2011-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2012-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20120126147-A |
| titleOfInvention |
Recombinant protein for delivery of siRNA and composition comprising same |
| abstract |
The present invention relates to a recombinant protein for siRNA delivery that enables efficient cellular and in vivo delivery of siRNA. More specifically, the present invention relates to a recombinant protein in which siRNA binding protein is located in an empty space inside a capsid protein of a Hepatitis B virus (HBV) virus, wherein siRNAs of various purposes bind to the siRNA binding protein and are encapsulated in a capsid internal space. As a result, stability can be ensured from external attack such as various enzymes, and siRNA can be effectively delivered to cells and living tissues by cytoplasmic release of siRNA after cell penetration. |
| priorityDate |
2011-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |