http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120125853-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4891 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 2011-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20120125853-A |
| titleOfInvention | An oleic acid-gelatin conjugate, a nanoparticle including the same, and a method preparing thereof |
| abstract | PURPOSE: A method for preparing a conjugate and nanoparticles is provided to ensure uniform particle distribution and high stability and to enhance solubility. CONSTITUTION: A conjugate for preparing drug delivery nanoparticles contains hydrophilic gelatin, and hydrophobic oleic acid conjugated with gelatin through amide bond. The conjugate further contains folic acid conjugated to the gelatin. A method for preparing gelatin and conjugate containing the gelatin and oleic acid comprises: a step of dissolving the gelatin in water to prepare a solution containing gelatin; and a step of adding colloidal water dispersion solution containing oleic acid and monoethanol amine to the solution containing gelatin. A method for preparing gelatin and a conjugate containing oleic acid and folic acid comprises: a step of dissolving the gelatin in the water to prepare a solution containing gelatin; a step of adding the colloidal water dispersion solution to the solution containing gelatin to prepare a solution containing the gelatin and a first conjugate with oleic acid conjugated with the gelatin; a step of drying and preparing the first conjugate from the solution; a step of adding a buffer solution to the first conjugate; and a step of imide compounds and folic acid to the buffer solution. [Reference numerals] (AA,EE,GG) Gelatin; (BB,FF,HH) Oleic acid; (CC,DD,II) Folic acid |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180097707-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210045133-A |
| priorityDate | 2011-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.