| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0622 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
| filingDate |
2011-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2012-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20120125331-A |
| titleOfInvention |
Engineered Biological Neuronal Grafts and Their Applications |
| abstract |
The engineered three-dimensional construct includes living cells in close contact with each other. Living cells suitably include Schwann cells and at least one other type of cell. The cells carrying Schwann cells may suitably be bone marrow stem cells or other types of cells with one or more anti-inflammatory properties. The construct is suitably a graft that facilitates regenerated axon growth when implanted between the distal stub and the proximal stub of the cut nerve in a living organism. The graft may optionally include a plurality of acellular afferent conduits extending between opposing ends along the axis of the graft. Using bioprinting techniques, three-dimensional constructs can be assembled by stacking a plurality of multicellular bodies, each comprising a plurality of living cells that are tight enough to avoid collapsing when the multicellular bodies are stacked to form a structure, This becomes an axon-derived graft through maturation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190095940-A |
| priorityDate |
2010-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |